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cathepsin |
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cathepsin /ca·thep·sin/ (kah-thep´sin) one of a number of enzymes each of which catalyzes the hydrolytic cleavage of specific peptide bonds. cathepsin a proteinase found in most cells, which takes part in cell autolysis and self-digestion of tissues. cathepsin D an acid hydrolase isolated from cartilage which plays a part in the endogenous degradation of proteoglycans in degenerative diseases of joints. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Baden notes that his team's experiments in mice showed that brevetoxins can also depress an animal's response to infection by inactivating cathepsins, enzymes that immune cells use to break down debris as they attack it. 1992); and c) cathepsins located within macrophages and B-lymphocytes play an important role in the formation of antigenic determinants essential for both humoral and cell-mediated immune responses (Katunuma et al. It turns out that people make seven cathepsins, whereas the parasite makes only two. |
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