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cathepsin |
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cathepsin /ca·thep·sin/ (kah-thep´sin) one of a number of enzymes each of which catalyzes the hydrolytic cleavage of specific peptide bonds. cathepsin a proteinase found in most cells, which takes part in cell autolysis and self-digestion of tissues. cathepsin D an acid hydrolase isolated from cartilage which plays a part in the endogenous degradation of proteoglycans in degenerative diseases of joints. |
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Axys is currently applying its chemistry and pharmacology expertise to this target, with an eye toward identification of lead compounds designed specifically for Cathepsin V for use in cancer therapy. of Axys stated, "The structure of Cathepsin V is invaluable in helping design potent and selective inhibitors against this therapeutically-relevant protease. The structure of Cathepsin V is invaluable in helping design potent and selective inhibitors against this therapeutically-relevant protease. |
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