Comparison of hypotensive and hypolipidemic effects of Catharanthus
roseus leaves extract with atenolol on adrenaline induced hypertensive rats.
Effect of oxygen and nutrient limitation on ajmalicine production and related enzyme activities in high density cultures of Catharanthus
Studies on germination, seedling vigor, lipid peroxidation and proline metabolism in Catharanthus
roseus seedlings under salt stress.
The first anticancer drugs approved for clinical use were the dimeric indole alkaloids vinblastine and vincristine, isolated from the Madagascar periwinkle, Catharanthus
Soil salinity alters growth, chlorophyll content, and secondary metabolite accumulation in Catharanthus
Differential responses in water use efficiency in two varieties of Catharanthus
roseus under drought stress.
The five anti-hypertensive plants were Catharanthus
roseus, Rauwolfia serpentina, Calotropis gigantea, Ficus religiosa, and Curcuma longa.
Effect of salinity and different nitrogen sources on the activity of antioxidant enzymes and indole alkaloid contents in Catharanthus
roseus flower extract has wound-healing activity in Sprague-Dawley rats.
The positive effects of organic manure and chemical fertilizers on seed yield and oil content are in agreement with previous reports for other medicinal plants, such as, Catharanthus
roseus , Cynbopogon winterianus , Pogostemon cablin , Plantago ovata , Ammi majus , P.
Nerium oleander Rhazya stricta and Vinca major were the most similar with a bootstrap value of 24-44 % while Catharanthus
roseus and Nerium oleander showed distant relationship.
Among others we can cite as plant-derived drugs, vincristine isolated from Catharanthus
roseus, paclitaxel isolated from Taxus brevifolia, irinotecan, which is a hemisynthetic derivative of camptothecin isolated from Camptotheca acuminata, and etoposide, which is a hemisynthetic derivative of a compound isolated from Podophyllum.