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catecholamine |
Also found in: Encyclopedia, Wikipedia, Hutchinson | 0.06 sec. |
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catecholamine /cat·e·chol·amine/ (kat?ah-kol´ah-men?) any of a group of sympathomimetic amines (including dopamine, epinephrine, and norepinephrine), the aromatic portion of whose molecule is catechol.
catecholamine (kat´ n any one of a group of sympathomimetic compounds composed of a catechol molecule and the aliphatic portion of amine. Some catecholamines (epinephrine and norepinephrine) are produced naturally by the body and function as key neurologic chemicals. catecholamine any of a group of sympathomimetic amines (including dopamine, epinephrine and norepinephrine), the aromatic portion of whose molecule is catechol. The catecholamines play an important role in the body's physiological response to stress. Their release at sympathetic nerve endings increases the rate and force of muscular contraction of the heart, thereby increasing cardiac output; constricts peripheral blood vessels, resulting in elevated blood pressure; elevates blood glucose levels by hepatic and skeletal muscle glycogenolysis; and promotes an increase in blood lipids by increasing the catabolism of fats. catecholamine-depleting agents cause depletion of neuronal stores of norepinephrine, thereby reducing adrenergic responses, e.g. reserpine. catecholamine Endocrinology A biogenic amine from tyramine/phenylalanine which contains a catechol nucleus Examples Epinephrine–adrenaline in UK, norepinephrine–noradrenaline and dopamine, which act as hormones and neurotransmitter in the peripheral and central nervous system; catecholamines are produced by sympathetic nervous system activation Activity Autonomic arousal, fight-or-flight stress response, reward response. See Biogenic amine, Dopamine, Epinephrine, Indolamine, Norepinephrine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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