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catecholamine |
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catecholamine /cat·e·chol·amine/ (kat″ah-kol´ah-mēn″) any of a group of sympathomimetic amines (including dopamine, epinephrine, and norepinephrine), the aromatic portion of whose molecule is catechol.
catecholamine [kat′əkəlam′in] any one of a group of sympathomimetic compounds composed of a catechol (1,2-dihydroxyphenyl) moiety carrying an alkyl side chain with an amine group on the side chain. Some catecholamines are produced naturally by the body and function as key neurologic chemicals. catecholamine (kat´ n any one of a group of sympathomimetic compounds composed of a catechol molecule and the aliphatic portion of amine. Some catecholamines (epinephrine and norepinephrine) are produced naturally by the body and function as key neurologic chemicals. catecholamine any of a group of sympathomimetic amines (including dopamine, epinephrine and norepinephrine), the aromatic portion of whose molecule is catechol. The catecholamines play an important role in the body's physiological response to stress. Their release at sympathetic nerve endings increases the rate and force of muscular contraction of the heart, thereby increasing cardiac output; constricts peripheral blood vessels, resulting in elevated blood pressure; elevates blood glucose levels by hepatic and skeletal muscle glycogenolysis; and promotes an increase in blood lipids by increasing the catabolism of fats. catecholamine-depleting agents cause depletion of neuronal stores of norepinephrine, thereby reducing adrenergic responses, e.g. reserpine. catecholamine Endocrinology A biogenic amine from tyramine/phenylalanine which contains a catechol nucleus Examples Epinephrine–adrenaline in UK, norepinephrine–noradrenaline and dopamine, which act as hormones and
neurotransmitter in the peripheral and central nervous system; catecholamines are produced by sympathetic nervous system activation Activity Autonomic arousal, fight-or-flight stress response, reward response. See Biogenic amine, Dopamine, Epinephrine, Indolamine, Norepinephrine. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The patients had blood concentrations of catecholamine hormones that were more than seven times normal and two to three times as great as those in five patients having heart attacks triggered by coronary artery blockages. |
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