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Cataplexy |
Also found in: Dictionary/thesaurus, Wikipedia, Hutchinson | 0.01 sec. |
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cataplexy /cat·a·plexy/ (kat´ah-plek?se) a condition marked by abrupt attacks of muscular weakness and hypotonia triggered by such emotional stimuli as mirth, anger, fear, etc., often associated with narcolepsy.cataplec´tic
Cataplexy A symptom of narcolepsy in which there is a sudden episode of muscle weakness triggered by emotions. The muscle weakness may cause the person's knees to buckle, or the head to drop. In severe cases, the patient may become paralyzed for a few seconds to minutes. Mentioned in: Narcolepsy, Sleep Disorders cataplexy a condition, often associated with narcolepsy; marked by abrupt attacks of a loss of voluntary muscular function (flaccid paralysis), except those controlling respiration and eye movement. Observed in dogs, cats and horses, especially Shetland ponies. In dogs these have been precipitated by extreme excitement, vigorous physical or sexual activity. Usually of short duration. Most cases are idiopathic, but can be associated with lesions of the brainstem. food-elicited cataplexy test cataleptic dogs demonstrate repeated attacks of catalepsy when presented with several individual pieces of food. |
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? Mentioned in | ? References in periodicals archive | |
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Cataplexy often occurs in response to strong emotions, such as surprise, anguish, or elation. Even if clear-cut narcolepsy is present, per an incontrovertible history of cataplexy, overnight sleep laboratory monitoring usually still is warranted, due to the high prevalence of sleep apnea: even as an aggravating factor that could render treatment for narcolepsy less efficacious. Xyrem has demonstrated an acceptable safety profile in narcoleptics with cataplexy when administered in nightly divided doses of 6 to 9 g with a recommended starting dose of 4. |
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