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caspofungin

   Also found in: Wikipedia 0.03 sec.
caspofungin /cas·po·fun·gin/ (kas″po-fun´jin) an antifungal used as the acetate salt in the treatment of invasive aspergillosis.
caspofungin
a beta-glucan synthase inhibitor used as a broad spectrum antifungal agent.


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On July 22, hospital treatment was initiated; it consisted of antimicrobial drug treatment with ceftriaxone (1,000 mg once daily) and gentamicin (320 mg once daily), and antimycotic therapy was started with caspofungin (50 mg once daily).
Susceptibility (minimal effective concentration) to caspofungin (Merck Research Laboratories, Rahway, NJ, USA) was determined by using a microbroth dilution assay in antibiotic 3 (AM3) media, as described previously (22).
Overall, the antifungal therapeutic market has been stagnating since the introduction of caspofungin (Mercks Cancidas) and voriconazole (Pfizers Vfend), both of which were approved in the United States in 2001.
 
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