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Cardiovascular Endpoint

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Cardiovascular Endpoint
An objective morbid condition or cause of death linked to cardiovascular disease, used as an indicator in a clinical trial or reportable event
Examples Cardiovascular death, nonfatal myocardial infarction, hospitalization for heart failure, increase in blood pressure, etc.


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During the 76-week treatment phase, the pre-specified adjudicated cardiovascular endpoint (defined as cardiovascular death, myocardial infarction, unstable angina or stroke) occurred in 16 anacetrapib-treated patients (2.
Recommendations published in December 2008 require sponsors to establish an independent cardiovascular endpoints committee to adjudicate cardiovascular events, including cardiac death, acute myocardial infarction and stroke.
Participants within the SMART study who had been randomised to continuous antiretroviral therapy (n=2752) were included in the analysis of cardiovascular events: either of myocardial infarction (MI) or of various composite cardiovascular endpoints.
 
 
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