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cardiotoxicity |
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| I don't think anyone would have expected this drug to have any cardiotoxicity," says Force. In collaboration with Frank Sistare, acting director of the Office of Testing and Research at the Food and Drug Administration Center for Drug Evaluation and Research, the team obtained preliminary results from a rat model showing that cardiotoxicity was detected 90% of the time before clinical symptoms occurred. The parties may jointly choose to expand the scope of the collaboration to include biomarkers for the detection of hepatotoxicity and/or cardiotoxicity in response to drug treatment. |
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