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Chief or principal; in embryology, relating to the main venous drainage.
[L. cardinalis, principal]


/car·di·nal/ (kahr´dĭ-n'l)
1. of primary or preeminent importance.
2. in embryology, pertaining to the main venous drainage.


Etymology: L, cardo, hinge
pertaining to something so fundamental that other things hinge on it, such as a cardinal trait that influences one's total behavior.


A gene on chromosome 19q13.33 that encodes a protein involved in apoptosis which is highly expressed in the lung, ovary, testis and placenta. CARD8 inhibits NF-kappa-B activation and regulates cell responses controlled by NF-kappa-B transcription factor. It may be part of the inflammasome, a protein complex that activates proinflammatory caspases.
References in periodicals archive ?
At Kelly's on Saturday they will be supported by Cardinal Red.
City Chic combines black, white and shades of pewter and steel with an accent of cardinal red.
He also recently sold the princess's cherished cardinal red Silver Wraith Rolls Royce, which she had owned for 22 years, netting pounds 20,000.
Ringaroses, a half-brother to Frosty Canyon and Cardinal Red, may not have had a lot to beat, and the winning margin over Nudge And Nurdle in the 2m5f novice contest was only a length and a half.
Q I need a new doormat on my porch's cardinal red tiled floor.
USC's ORIGINAL SCHOOL COLOR was gold and the College of Liberal Arts was cardinal red.
Death Is Inevitable, 2008--a flat composition of cardinal red, fringelike (or tonguelike) concentric squares licking inward toward a blank, stark white ground--also hung in the main gallery, further emphasizing Kusama's practiced attention to negative space.