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Chief or principal; in embryology, relating to the main venous drainage.
[L. cardinalis, principal]


/car·di·nal/ (kahr´dĭ-n'l)
1. of primary or preeminent importance.
2. in embryology, pertaining to the main venous drainage.


Etymology: L, cardo, hinge
pertaining to something so fundamental that other things hinge on it, such as a cardinal trait that influences one's total behavior.


A gene on chromosome 19q13.33 that encodes a protein involved in apoptosis which is highly expressed in the lung, ovary, testis and placenta. CARD8 inhibits NF-kappa-B activation and regulates cell responses controlled by NF-kappa-B transcription factor. It may be part of the inflammasome, a protein complex that activates proinflammatory caspases.
References in periodicals archive ?
If you only know cannas as tall, cardinal red, massive plants, you need to become acquaint-ed with the container-sized plants in pastels and the variegated foliage types such as pretoria, striped beauty and stuttgart.
We Trojans were cardinal red about this, since USC had spanked Alabama on Alabama's own field that season.
Both the toasters and kettles will eventually be available in velvet blue and cardinal red, in addition to the initial toaster launch in pearl or carbon gray and steel.
The first horse de Haan believed capable of lifting his career was Cardinal Red, a smart performer who joined him on Mrs Walwyn's retirement and then finished a creditable seventh in the 1994 Stayers' Hurdle.
In fact, he has just one, Cardinal Red, which we attribute to The Parson genes.
Tina Ike stood amid a sea of cardinal red and gold, and just beamed.
In table linens, colors are deep and powerful including hickory clay, spice, indigo and cardinal red.
Gaelstrom's finest moment among eight wins over hurdles and fences was her defeat of Cardinal Red and Lord Relic in the 1993 Sun Alliance Hurdle.