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stiff heart syndrome
(redirected from Cardiac amyloidosis)

   Also found in: Wikipedia 0.12 sec.
stiff heart syndrome
Cardiology A nonspecific term for ventricular pump failure due to restrictive heart disease Clinical Chest pain, exertional dyspnea, ↑ venous pressure, extra-diastolic murmurs, hepatomegaly, ascites, edema Etiology Idiopathic, or related to amyloidosis, constrictive pericarditis due to radiation, mycosis, trauma, TB, hemochromatosis, myocardiopathy. Cf 'Stone' heart.


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2) Endomyocardial biopsy, though invasiye, is indicated in patients with suspected cardiac amyloidosis and unexplained diastolic heart failure, especially when extracardiac tissue is negative for amyloid.
A mutation in transthyretin is not a prerequisite for the development of transthyretin-associated cardiac amyloidosis.
As soon as cardiac amyloidosis is suspected, prompt diagnosis is essential.
 
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