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carboxyhemoglobin |
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carboxyhemoglobin /car·boxy·he·mo·glo·bin/ (-he´mo-glo″bin) hemoglobin combined with carbon monoxide, which occupies the sites on the hemoglobin molecule that normally bind with oxygen and which is not readily displaced from the molecule.
Carboxyhemoglobin (COHb) Hemoglobin that is bound to carbon monoxide instead of oxygen. Mentioned in: Carbon Monoxide Poisoning carboxyhemoglobin [kärbok′sēhē′məglō′bin, -hem′-] Etymology: L, carbo + Gk, oxys, sharp, haima, blood; L, globus, ball a compound produced by the exposure of hemoglobin to carbon monoxide. Carbon monoxide from the environment is inhaled into the lungs, absorbed through the alveoli, and bound to hemoglobin in the blood, blocking the sites for oxygen transport. Oxygen levels decrease, and hypoxia and anoxia may result. Also spelled carboxyhaemoglobin. See also carbon monoxide poisoning, oxyhemoglobin. carboxyhemoglobin hemoglobin combined with carbon monoxide, which occupies the sites on the hemoglobin molecule that normally bind with oxygen and which is not readily displaced from the molecule; exposure to carbon monoxide thus results in cellular anoxia. See also hemoglobin. carboxyhemoglobin COHb Hb in which carbon monoxide–CO is irreversibly bound How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Exposure to CO can be assessed by measuring the carboxyhemoglobin adduct (Shenoi et al. Smoking may add to exercise and activity limitation by increasing carboxyhemoglobin content and subsequently reducing the oxygen-carrying content capacity in the blood. COHb stands for carboxyhemoglobin, the measurement of carbon monoxide in the subject's blood. |
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