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carboxyhemoglobin
(redirected from Carboxyhaemoglobin)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
carboxyhemoglobin /car·boxy·he·mo·glo·bin/ (-he´mo-glo″bin) hemoglobin combined with carbon monoxide, which occupies the sites on the hemoglobin molecule that normally bind with oxygen and which is not readily displaced from the molecule.
car·box·y·he·mo·glo·bin (kär-bks-hm-glbn)
n.
The compound that is formed when inhaled carbon monoxide combines with hemoglobin in the blood. Also called carbon monoxide hemoglobin.

Carboxyhemoglobin (COHb)
Hemoglobin that is bound to carbon monoxide instead of oxygen.

carboxyhemoglobin
[kärbok′sēhē′məglō′bin, -hem′-]
Etymology: L, carbo + Gk, oxys, sharp, haima, blood; L, globus, ball
a compound produced by the exposure of hemoglobin to carbon monoxide. Carbon monoxide from the environment is inhaled into the lungs, absorbed through the alveoli, and bound to hemoglobin in the blood, blocking the sites for oxygen transport. Oxygen levels decrease, and hypoxia and anoxia may result. Also spelled carboxyhaemoglobin. See also carbon monoxide poisoning, oxyhemoglobin.

carboxyhemoglobin [kahr-bok″se-he´mo-glo″bin]
hemoglobin in which the sites usually bound to oxygen are bound to carbon monoxide molecules; carbon monoxide has an affinity for hemoglobin over 200 times that of oxygen. See carbon monoxide poisoning.

carboxyhemoglobin
hemoglobin combined with carbon monoxide, which occupies the sites on the hemoglobin molecule that normally bind with oxygen and which is not readily displaced from the molecule; exposure to carbon monoxide thus results in cellular anoxia. See also hemoglobin.

carboxyhemoglobin
COHb Hb in which carbon monoxide–CO is irreversibly bound


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Carbon monoxide exposure results in increased carboxyhaemoglobin, leading to a reduction in placental oxygen delivery, and causes low birth weight and an increase in perinatal death.
This dose equivalence is consistent with the reported three to fivefold greater levels of carboxyhaemoglobin (a marker of carbon monoxide exposure) and tar inhaled when smoking a cannabis joint compared with a tobacco cigarette of the same size.
 
 
 
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