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One of a class of indole alkaloids structurally similar to the amino acid L-tryptophan, when ingested, maycause hallucinations.
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The combination of MAO inhibitors such as some ayahuasca j carbolines with monoaminergic and serotoninergic substances in general, antidepressives, as well as ginseng, St John's wort, dextromethorphan, amphetamine, and 3,4-methylenedioxymethamphetamine (MDMA: "ecstasy"), could produce the serotonin syndrome (dos Santos 2013a; Pilgrim et al.