carbogen


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car·bo·gen

(kar'bō-jen),
A mixture of 10% carbon dioxide and 90% oxygen used for inhalation therapy to produce vasodilation.
[carbon dioxide + oxygen]

carbogen

An inhalant of O2 and CO2. Meduna’s original formulation called for 30% CO2 and 70% O2, but the term has been genericised and now refers to any CO2 concentration from 1.5% to 50%. The brain responds to increased CO by increasing breathing and heart rates.

Fringe psychiatry
Carbogen was used in psychedelic therapy in combination with LSD, psilocybin, DMT and 2C-B to ensure a smoother, more profound experience; hallucinogenic psychotherapy remains outside of mainstream medicine.
  
Oncology
The carbogen used in oncology is a mixture of 95% O2 and 5% CO2 and inhaled as a therapeutic adjunct, based on the premise that because tumours thrive in hypoxic conditions, increasing tumour oxygenation during radiotherapy or chemotherapy should increase tumour susceptibility to the therapy. It is considered investigational and is not reimbursed by BlueCross and BlueShield.

Psychiatric history
Meduna used carbogen to assess whether to manage patients with psychotherapeutics; those who reacted poorly to the altered state of consciousness induced by carbogen were de-selected for psychotherapeutic drugs, given the concern that they might evoke a similar response.

car·bo·gen

(kahr'bō-jen)
A mixture of 10% carbon dioxide and 90% oxygen used for inhalation therapy to produce vasodilation.
[carbon dioxide + oxygen]
References in periodicals archive ?
Improvement of tumor oxygenation status by mild temperature hyperthermia alone or in combination with carbogen.
Before and about an hour after each dose, the patients briefly breathed carbogen gas (95% oxygen, 5% carbon dioxide) to induce hypercapnia and subsequent cerebral vasodilation.
measured submacular choroidal and optic nerve head blood flow, fundus pulsation amplitudes, and retinal vessel diameters during and after carbogen (5% C[O.
Human tumour blood flow is enhanced by nicotinamide and carbogen breathing.
1992) Retinal effects of carbogen dioxide, hyperoxia, and mild hypoxia.
The initial collaboration is with Swiss-based pharmaceutical process development and API manufacturers Carbogen AMCIS AG - an established global player in high-potency and anti-cancer drug production.
Management of the DER includes supportive measures to restore blood pressure and to treat shock including oxygen, carbogen, intravenous vitamin C and ephedrine sulfate.
All were treated with bed rest, steroids, magnesium, and carbogen inhalation.
A collection of pre-clinical animal studies published in the Journal of Medicinal Food in October 2011 confirms that adding Triarco's patented Carbogen enzyme system to a meal replacement bar increased the rate of glucose absorption.
At CARBOGEN AMCIS, the required containment level is determined based on the substance's pharmacological and toxicological activity, and the exposure potential of the anticipated unit operations, leading to a performance-based exposure control limit or occupational exposure limit in cases where sufficient toxicological data exist.
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