carbapenem


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carbapenem

(kahr-bă-pen'em),
Member of a class of antibiotic drugs that works by inhibiting cell wall synthesis.

carbapenem

(kär′bə-pĕn′əm)
n.
Any of several semisynthetic or synthetic beta-lactam antibiotics that are used chiefly to treat serious infections caused by bacteria that are resistant to other antibiotics.

carbapenem

A class of antibiotics with a broad spectrum of action against gram-positive, gram-negative, and anaerobic germs. The carbapenems include imipenem and meropenem.
References in periodicals archive ?
A total of five carbapenem resistant clinical isolates including Escherichia coli (n=1), Klebsiella pneumoniae (n=1), Enterobacter cloacae (n=1), Acinetobacter baumannii (n=1) and Pseudomonas aeruginosa (n=1) were isolated from the blood cultures of patients hospitalized in a tertiary care hospital of Lahore, Pakistan.
Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem resistance in Pseudomonas aeruginosa , but use of the high-potency drug doripenem inhibits mutant formation.
The overall resistance to carbapenem was 95(95%); it was higher 100 (100%) in Acinetobacter lwoffii in comparison to Acinetobacter calcoaceticus-baumannii complex 90 (94.
It started when a group of five patients in the intensive care unit at a hospital in the Chinese city Hangzhou, who all had trauma surgery, contracted severe pneumonia that did not respond to antibiotics called carbapenems, which are generally used as a last resort when other treatments fail.
Inhibition mechanism of carbapenem antibiotics on acylpeptide hydrolase, a key enzyme in the interaction with valproic acid.
The study was carried out to screen and characterize carbapenem resistance encoding genes among Gram negative bacteria from Urinary Tract Infection in patients with type 2 diabetes mellitus
We used this infrastructure to observe national trends of carbapenem resistance and nonsusceptibility in K.
Risk factors associated with pneumonia for Klebsiella pneumoniae carbapenem resistant).
NDM]) (27-29), and carbapenem hydrolyzing oxacillinases ([bla.
Zavicefta specifically addresses multi-drug resistant Gram-negative infections, including those resistant to carbapenem antibiotics, which represents significant unmet medical needs in bacterial infections.
baumannii isolates, cefoperazone-sulbactam demonstrated good antimicrobial activities, except those were carbapenem resistant and which may provide another therapeutic option for treating MDRGNBs.