A total of five carbapenem
resistant clinical isolates including Escherichia coli (n=1), Klebsiella pneumoniae (n=1), Enterobacter cloacae (n=1), Acinetobacter baumannii (n=1) and Pseudomonas aeruginosa (n=1) were isolated from the blood cultures of patients hospitalized in a tertiary care hospital of Lahore, Pakistan.
Fluoroquinolone enhances the mutation frequency for meropenem-selected carbapenem
resistance in Pseudomonas aeruginosa , but use of the high-potency drug doripenem inhibits mutant formation.
The overall resistance to carbapenem
was 95(95%); it was higher 100 (100%) in Acinetobacter lwoffii in comparison to Acinetobacter calcoaceticus-baumannii complex 90 (94.
It started when a group of five patients in the intensive care unit at a hospital in the Chinese city Hangzhou, who all had trauma surgery, contracted severe pneumonia that did not respond to antibiotics called carbapenems
, which are generally used as a last resort when other treatments fail.
Inhibition mechanism of carbapenem
antibiotics on acylpeptide hydrolase, a key enzyme in the interaction with valproic acid.
The study was carried out to screen and characterize carbapenem
resistance encoding genes among Gram negative bacteria from Urinary Tract Infection in patients with type 2 diabetes mellitus
We used this infrastructure to observe national trends of carbapenem
resistance and nonsusceptibility in K.
Risk factors associated with pneumonia for Klebsiella pneumoniae carbapenem
NDM]) (27-29), and carbapenem
hydrolyzing oxacillinases ([bla.
Zavicefta specifically addresses multi-drug resistant Gram-negative infections, including those resistant to carbapenem
antibiotics, which represents significant unmet medical needs in bacterial infections.
baumannii isolates, cefoperazone-sulbactam demonstrated good antimicrobial activities, except those were carbapenem
resistant and which may provide another therapeutic option for treating MDRGNBs.
4] Indian single centre studies showed a prevalence of Carbapenem
resistance was 12-15% of Enterobacteriaceae.