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carbachol |
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carbachol /car·ba·chol/ (kahr´bah-kol) a cholinergic agonist used as a miotic and to lower intraocular pressure in the treatment of glaucoma and following cataract surgery.
carbachol a potent choline ester with muscarinic and nicotinic effects including defecation, slowing of the heart, urination and respiratory restriction due to bronchiolar constriction.
parasympathomimetic drug A drug with an action resembling that caused by stimulation of the parasympathetic nervous system. Example: a miotic of which there are two types: a direct-acting cholinergic, such as pilocarpine or carbachol; and the other, indirect-acting anticholinesterase, such as physostigmine, neostigmine, echothiophate iodide, demecarium bromide. Syn. cholinergic drug. See miotics.
carbachol A parasympathomimetic formed by substituting an acetyl with a carbamyl group on acetylcholine, which acts on muscarinic and nicotinic receptors How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Pulmonary function tests showed a reduced diffusing capacity of 67% predicted with oxygen desaturation on ambulation (Table 1), and a carbachol challenge (a test for airway hyperreactivity in asthma) was negative. Carbachol, a muscarinic agonist, appropriately reduced both the basal and isoprenaline-induced contractile frequency, demonstrating appropriate muscarinic receptor activity as well. Airway responsiveness to carbachol was determined from cumulative concentration-response curves as previously described (Abraham et al. |
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