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CAPRIE |
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CAPRIE Clopidogrel vs. Aspirin in Patients at Risk of Ischemic Events. A trial comparing an antiplatelet agent, clopidogrel, to aspirin in decreasing the risk of stroke, infarction, or vascular death in patients with evidence of vascular disease
Conclusion Long-term clopidogrel is more effective than aspirin in decreasing composite end-points for patients with symptomatic ASHD; clopidogrel’s safety is comparable to medium dose aspirin CAPRIE Cardiology A clinical trial–Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events which compared the efficacy of the antiplatelet agent, clopidogrel, with aspirin therapy as a stroke prophylaxis. See Clopidogrel. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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The CAPRIE trial (42) studied 19,000 patients with stroke, MI, or peripheral vascular disease and showed only a modest, 8. In the CURE trial, patients with unstable angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI) receiving Plavix([R])with aspirin were followed for up to one year, and in the CAPRIE trial, patients with recent MI, recent ischemic stroke, or established peripheral artery disease receiving Plavix([R])alone were followed for up to three years. However, Prasugrel has to go through an intensive Phase III clinical program to translate the better platelet inhibition seen in Phase I studies to improved clinical outcomes in terms of reducing MI and other CAD instances and death compared to Clopidogrel - essentially an expensive and time consuming study similar to CAPRIE study done for establishing Clopidogrel's marginal superiority over Aspirin. |
CAPRIE |
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