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capreomycin

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capreomycin /cap·reo·my·cin/ (kap″re-o-mi´sin) a polypeptide antibiotic produced by Streptomyces capreolus, which is active against human strains of Mycobacterium tuberculosis ; used as the disulfate salt.
cap·re·o·my·cin (kpr--msn)
n.
An antibiotic derived from Streptomyces capreolus and effective against the microorganism responsible for tuberculosis in humans.

capreomycin
[kap′rē·ōmī′sin]
an antibiotic and antitubercular agent.
indications It is prescribed in the treatment of pulmonary infections caused by capreomycin-susceptible strains of Mycobacterium tuberculosis when the primary agents are ineffective or cannot be used.
contraindications Known sensitivity to this drug prohibits its use. It must be used with caution in patients with preexisting renal or auditory impairment.
adverse effects Among the most serious adverse reactions are nephrotoxicity, hearing loss, tinnitus, vertigo, leukocytosis, leukopenia, urticaria, and skin rash.

capreomycin [kap″re-o-mi´sin]
a polypeptide antibiotic produced by Streptomyces capreolus, which is active against human strains of Mycobacterium tuberculosis; used as the disulfate salt.

capreomycin
Infectious disease An antibiotic used to treat MAC and TB Side effects Anorexia, thirst, excess urination, hematuria, anemia, hearing loss. See AIDS.


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Examples of drugs known or reported to be ototoxic Ototoxic drug class Examples Aminoglycosides Streptomycin, amikacin, tobramycin, gentamycin, kanamycin, capreomycin Platinum-based chemotherapy Cisplatin, carboplatin, oxaliplatin Loop diuretics Furosemide, torasemide, bumetanide, piratenide Other antibiotics Erythromycin, vancomycin Antimalarials Quinine Salicylates Aspirin Phosphodiesterase type Sildenafil, tadalafil, vardenafil 5 inhibitors
In October 2006, the WHO was forced to revice the MDR definition when a new strain appeared that was resistant to second-and even third-line drugs--the fluoroquinolones and the injectable drugs amikacin, capreomycin, and kanamycin.
The plant also produces capreomycin, an antibiotic used to treat multi-drug resistant tuberculosis.
 
 
 
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