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capreomycin

   Also found in: Dictionary/thesaurus, Wikipedia 0.04 sec.
capreomycin /cap·reo·my·cin/ (kap″re-o-mi´sin) a polypeptide antibiotic produced by Streptomyces capreolus, which is active against human strains of Mycobacterium tuberculosis ; used as the disulfate salt.
cap·re·o·my·cin (kpr--msn)
n.
An antibiotic derived from Streptomyces capreolus and effective against the microorganism responsible for tuberculosis in humans.

capreomycin
[kap′rē·ōmī′sin]
an antibiotic and antitubercular agent.
indications It is prescribed in the treatment of pulmonary infections caused by capreomycin-susceptible strains of Mycobacterium tuberculosis when the primary agents are ineffective or cannot be used.
contraindications Known sensitivity to this drug prohibits its use. It must be used with caution in patients with preexisting renal or auditory impairment.
adverse effects Among the most serious adverse reactions are nephrotoxicity, hearing loss, tinnitus, vertigo, leukocytosis, leukopenia, urticaria, and skin rash.

capreomycin
Infectious disease An antibiotic used to treat MAC and TB Side effects Anorexia, thirst, excess urination, hematuria, anemia, hearing loss. See AIDS.


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Susceptibility to first-line (streptomycin, isoniazid, rifampin, and ethambutol) and second-line (kana-mycin, ethionamide, capreomycin, cycloserine, p-aminosalicylic acid, and ofloxacin) drugs was determined by the proportion method on Middlebrook 7H10 agar.
The anti-TB medications included in the screening were isoniazid, rifampin, pyrazinamide, ethambutol, streptomycin, ethionamide, kanamycin, cycloserine, capreomycin, paraaminosalicylic acid (PAS), and drugs containing any combination of these medications.
Returned to West Africa after 4 months DOT C INH, rifampin, PZA, and Sputum culture and smear ethambutol by DOT for 6 negative, chest months radiograph improved D Capreomycin, ofloxacin, Sputum smear and culture PAS, clofazamine, and converted to negative, cycloserine for 2 y by symptoms resolved.
 
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