cannabinoid receptor


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cannabinoid receptor

THC receptor, see there.
References in periodicals archive ?
In neurons, DHA can be directly converted into Synaptamide (Docosahexaenoylethanolamide), a structural analog of the endogenous cannabinoid receptor ligand anandamide, made from Arachidonic Acid.
9) Synthetic cannabinoids often have more potent effects than natural marijuana, as the synthetic cannabinoids bind the cannabinoid receptor with higher affinity.
This is in large part due to the growth in the use of synthetic cannabinoid receptor agonists including Spice, which are often mistakenly described as legal highs.
The analgesic effects of cannabinoids and their ligands are primarily mediated by the cannabinoid receptor 1 (CB1) via inhibition of presynaptic gamma-aminobutyric acid (GABA) and glutamatergic transmission.
We didn't know how cannabis worked within the body until 1988, when the cannabinoid receptor was discovered, suggesting that there is this whole regulatory or modulatory system we didn't know anything about.
For example, terpenes, the molecules responsible for marijuana's smell, have been shown to block some cannabinoid receptor sites in the brain, while promoting cannabinoid binding in others.
Articles were included if they met the following criteria: 1) in vitro studies that established a clear association between cannabinoid receptor activation or inactivation and subsequent effect on tumour activity; 2) in vivo studies that explored the effect on THC administration either locally or systemically on tumour activity and/or size; and 3) all study types were included except expert opinion pieces.
UR-144 is a synthetic cannabinoid receptor agonist (SCRA) and has an affinity for CB1 and CB2 receptors.
Eleven different SC chemicals ([dagger]) were identified among product and paraphernalia samples collected at hospital A, the most common being AB-CHMINACA, MAB-CHMINACA, and 5F-AMB, all highly potent cannabinoid receptor agonists (7,8).
If this observation is confirmed in independent studies, further investigation into the possible therapeutic benefit of cannabinoid receptor agonists in acute MI may be warranted," declared Dr.
CB1 is the primary cannabinoid receptor in the nervous system, and its activation accounts for most of the neurobehavioral effects of THC.