fluvastatin(redirected from Canef)
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fluvastatin/flu·va·stat·in/ (floo´vah-stat″in) an inhibitor of cholesterol biosynthesis used as the sodium salt in the treatment of hyperlipidemia and to slow the progression of atherosclerosis associated with coronary heart disease.
A statin, C24H26FNO4, used in the form of its sodium salt, that blocks the body's synthesis of cholesterol and is administered especially to individuals who are at risk for heart disease.
indications It is used as an adjunct treatment in primary hypercholesterolemia (types Ia and Ib) and in coronary atherosclerosis associated with coronary artery disease.
contraindications Factors that prohibit its use include known hypersensitivity to this drug, pregnancy, lactation, and active liver disease.
adverse effects Life-threatening effects are liver dysfunction, myositis, rhabdomyolysis, thrombocytopenia, hemolytic anemia, and leukopenia. Other adverse effects include rash, pruritus, nausea, constipation, diarrhea, dyspepsia, flatus, pancreatitis, lens opacities, myalgia, headache, dizziness, insomnia, fatigue, influenza, upper respiratory infection, rhinitis, cough, pharyngitis, and sinusitis.