BCG vaccine

(redirected from Calmette-Guerin vaccine)
Also found in: Dictionary, Encyclopedia.
Related to Calmette-Guerin vaccine: bacillus Calmette-Guerin, bacille Calmette-Guérin vaccine

BCG vaccine

 
bacille calmette-guérin vaccine, a tuberculosis vaccine containing living, avirulent, bovine-strain tubercle bacilli (Mycobacterium bovis). It may be administered percutaneously by a special technique using a multiple-puncture disk, intracutaneously, or intradermally, and it cannot be given when the patient is reactive to tuberculin, when acute infectious disease is present, or when there is extensive skin disorder. It offers some protection against tuberculosis but cannot be relied on for total control of the disease. In a high percentage of cases the vaccine causes local ulcers at the site of administration. Public health officials in the United States recommend the use of BCG vaccine only for those persons living in communities having a high rate of tuberculosis cases. After vaccination with BCG, the patient will have a positive response to tuberculin tests. See also BCG solution.

BCG vac·cine

a suspension of an attenuated strain (bacillus Calmette-Guérin) of Mycobacterium tuberculosis, bovine type, which is inoculated into the skin for tuberculosis prophylaxis.

BCG vaccine

(bē′sē-jē′)
n.
A preparation consisting of attenuated human tubercle bacilli that is used for immunization against tuberculosis.

BCG vaccine

BCG vaccine

A vaccine containing Bacille Calmette-Guérin, an attenuated strain of the bovine tubercle bacillus. The vaccine is used to confer a measure of immunity on people who, on Mantoux or Heaf testing are shown not to have had a primary infection with tuberculosis. It is equally effective in giving protection against leprosy. BCG vaccine is available in a freeze-dried form. The drug is on the WHO official list. (Leon Charles Albert Calmette, 1863–1933, French surgeon, and Camille Guerin, 1872–1961, French veterinary surgeon).

Calmette,

Leon Charles Albert, French bacteriologist, 1863-1933.
Bacille bilié de Calmette-Guérin - an attenuated strain of Mycobacterium bovis used for immunization against tuberculosis and in cancer chemotherapy. Synonym(s): Bacille Calmette-Guérin; Calmette-Guérin bacillus
Bacille Calmette-Guérin - Synonym(s): Bacille bilié de Calmette-Guérin
bacillus Calmette-Guérin vaccine - a vaccine for tuberculosis prophylaxis. Synonym(s): BCG vaccine
Calmette test - conjunctival reaction to tuberculin.
Calmette-Guérin bacillus - Synonym(s): Bacille bilié de Calmette-Guérin
Calmette-Guérin vaccine - Synonym(s): bacillus Calmette-Guérin vaccine

BCG

bacille Calmette-Guérin, an avirulent strain of Mycobacterium bovis.

BCG test
is sometimes used in the diagnosis of tuberculosis in dogs as being more reliable and sensitive than tuberculin testing.
BCG vaccination
has been used in the control of tuberculosis in cattle but has many disadvantages, especially interference with tuberculin testing, and is not recommended for use unless the prevalence of the disease is very high.
BCG vaccine
contains living BCG organisms. It was developed for use in the control of tuberculosis in humans. Contains living BCG organisms. Is used as a nonspecific stimulant to antibody production in chronic diseases, e.g. equine sarcoid and neoplasia in dogs.
References in periodicals archive ?
Non-specific effect of Bacille Calmette-Guerin vaccine on the immune response to routine immunisations.
Intralesional bacille Calmette-Guerin vaccine has been tried for metastatic disease.
bovis can be prevented by the injectable Bacille Calmette-Guerin vaccine, or BCG.
Meanwhile, the NHS was concentrating available supplies of the Bacillus Calmette-Guerin vaccine on higher-risk groups, with selective neonatal immunisation of infants at higher risk of exposure to TB.
In January 2008 the Indian government cancelled the licenses of three vaccine-producing units - the Central Research Institute, the Bacillus Calmette-Guerin Vaccine Laboratory and the Pasteur Institute of India - on account of non-compliance with Good Manufacturing Practices (GMP).
Having read it from cover to cover, the Pontypridd lad was inspired to embark on a long career in palliative paediatric care, which would see him travel the Third World helping to administer the lifesaving bacillus Calmette-Guerin vaccine.