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Calcium channel blocker |
Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia, Hutchinson | 0.03 sec. |
Calcium channel blocker A drug that relaxes blood vessels and lowers blood pressure. Mentioned in: Heart Failure, Hypertrophic Cardiomyopathy calcium channel blocker a drug, such as nifedipine or verapamil, that selectively blocks the influx of calcium ions through a specific ion channel (the slow channel or calcium channel) of cardiac muscle and smooth muscle cells; used in the treatment of cardiac arrhythmias. Calcium channel blockers act to control arrhythmias by slowing the rate of sinoatrial (SA) node discharge and the conduction velocity through the atrioventricular (AV) node. Called also calcium blocker, calcium antagonist. |
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| The company's major products include Atelec, a long-acting calcium channel blocker and Epadel, a treatment for hyperlipidemia. Food and Drug Administration (FDA) for a fixed dose combination of two antihypertensives, the calcium channel blocker (CCB) amlodipine besylate (currently marketed by Pfizer as Norvasc) and the angiotensin receptor blocker (ARB) olmesartan medoxomil, or Benicar. 3) Use of calcium channel blocker Outcome, predictor No (n = 427) (b) Yes (n = 70) (b) [Log. |
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