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calcitriol |
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calcitriol /cal·ci·tri·ol/ (kal″sĭ-tri´ol) 1. see dihydroxycholecalciferol. 2. a preparation of this compound, used in the treatment of hypocalcemia, hypophosphatemia, rickets, and osteodystrophy associated with a variety of disorders. calcitriol [kalsit′rē·ôl] the active form of vitamin D, a regulator of calcium metabolism. indication It is prescribed in the management of hypocalcemia in patients undergoing chronic renal dialysis and in patients with hypoparathyroidism. contraindications Hypercalcemia, evidence of vitamin D toxicity, malabsorption syndrome, decreased renal function, or known sensitivity to this drug prohibits its use. adverse effects Among the more serious adverse reactions are renal toxicity and those associated with hypercalcemia, such as soft tissue calcification. calcitriol (kal´sitri´ol), n brand name: Calcijex; drug class: vitamin D3 hormone; action: increases intestinal absorption of calcium and phosphorus; uses: hypocalcemia in chronic renal dialysis and rickets, nutritional supplement. calcitriol a nonproprietary name for 1,25-dihydroxycholecalciferol; used as a calcium regulator in the management of hypocalcemia. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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A one-year study of 15 people with MS to test the safety of a form of vitamin D called calcitriol found participants having fewer exacerbations during the study than before it began, although the study was not designed to test this outcome. In addition to systemic symptoms and hypercalcemia (a result of the production of high levels of calcitriol by activated macrophages), local symptoms may include sinusitis, lymphadenopathy, hearing loss, facial nerve palsy, and dysphonia. Management of post-transplant bone disease involves regular bone mineral densitometry assessment, administration of anti-resorptive agents such as calcitriol or bisphosphanates, and the maintenance of good nutrition, physical exercise and normal body weight. |
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