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Calcitonin |
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calcitonin /cal·ci·to·nin/ (-to´nin) a polypeptide hormone secreted by C cells of the thyroid gland, and sometimes of the thymus and parathyroids, which lowers calcium and phosphate concentration in plasma and inhibits bone resorption. Preparations (c.-human, c.-salmon) are used in the treatment of osteitis deformans, postmenopausal osteoporosis, and hypercalcemia.
Calcitonin A hormone produced by the parafollicular cells (C cells) of the thyroid. The main function of the hormone is to regulate calcium levels in body serum. calcitonin (kal·si·tōˑ·nin), n hormone originating in the thyroid's parafollicular cells; plays a role in calcium blood level regulation and serves to stimulate bone mineralization. calcitonin (kal´sitō´nin), n brand names: Calcitonin, Calcimar, Miacalcin; drug class: synthetic polypeptide calcitonins; action: inhibits bone resorption, reduces osteoclast function, reduces serum calcium levels in hypercalcemia; uses: Paget's disease, postmenopausal osteoporosis, hypercalcemia. calcitonin a polypeptide hormone secreted by the parafollicular or C cells of the thyroid gland, which is involved in plasma calcium homeostasis. It acts to decrease the rate of bone resorption. Called also thyrocalcitonin. calcitonin gene-related peptides potent vasodilators widely distributed in periadventitial nerves of blood vessels, sinoatrial and atrioventricular nodes, sensory neurons and the central nervous system generally. calcitonin-secreting cells parafollicular cells of the thyroid gland. |
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| In women who are more Brand name: than 5 years beyond Miacalcin menopause, calcitonin slows bone loss, increases spinal bone density and may relieve the pain asso- ciated with bone fractures. The Food and Drug Administration has approved five medications to treat or prevent osteoporosis: estrogen replacement therapy, alendronate (Fosamax), raloxifene (Evista), risedronate (Actonel), and calcitonin (Calcimar). Oncogene and calcitonin testing for medullary carcinoma of the thyroid was negative. |
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