2 :Dermatosis in Epilepsy Dermatosis Total Cafe-au-lait spots
2 Adenoma sebaceum 2 Acne vulgaris 2 Leuconychia 1 Gum hyperplasia 1 Linear scar 1 Tinea cruris 2 Total 11 Table.
are less common in NF2 than in NF1; only about one-third of NF2 patients have them.
5, 6) The classic clinical characteristics of NF1 include cafe-au-lait spots
, neurofibroma and several bony anomalies.
RAG 11 / M growth retardation 8 -- cafe-au-lait spots
radial ray defects (thumbs) pallor bruising and epistaxis hepatomegaly (5cm) splenomegaly (8cm) cafe-au-lait spots
growth retardation microcephaly 2.
Cutaneous and plexiform fibromas, cafe-au-lait spots
, and optic gliomas are common findings in this hereditary condition.
The most common are cafe-au-lait spots
- coffee-coloured marks found anywhere on the body - moles and bluish-grey Mongolian spots.
The diagnostic criteria typically include two or more of the following: six or more cafe-au-lait spots
, two or more neurofibromas or at least one plexiform fibroma, freckling in the axilla or inguinal region, a tumor of the optic pathway, two or more Lisch nodules, a distinctive osseous lesion, or a first-degree relative with neurofibromatosis type 1.
Some authors have reported an association of juvenile xanthogranuloma with cafe-au-lait spots
and a family history of neurofibromatosis type 1 or type 2.
The green light, in contrast, is used for the treatment of benign brown pigmented lesions, such as cafe-au-lait spots
, the "old age" spots commonly found on the backs of the hands, and lentigines or freckles.