CAFE

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Conduit Artery Function Evaluation. A substudy of the Anglo-Scandinavian Cardiac Outcomes Trial, which compared the beta blocker atenolol, with or without a diuretic, with a regimen based on amlodipine with or without the ACE inhibitor perindopril. CAFE showed reductions in central aortic BP with amlodipine + perindopril over atenolol + diuretic, despite similar brachial BPs between groups assessing the safety and efficacy of the PercuSurge Guardwire (PSG) distal occlusion system in carotid stent supported angioplasty
Primary endpoints Clinical events at 30 days
Conclusion Carotid stenting with distal protection using PSG is safe and has a high clinical, angiographic, and device success rate