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In the study to be published in the journal eLife, the TSRI-led team administered an antidepressant called mianserin to Caenorhabditis elegans, a type of roundworm used frequently in research.
Shana McCormack et al, "Pharmacologic targeting of sirtuins and PPAR signaling improves longevity and mitochondrial physiology in respiratory chain complex I mutant Caenorhabditis elegans," Mitochondrion, published online March 3, 2015 and in May 2015 print issue.
Ameliorative effect of aspalathin from rooibos (Aspalathus linearis) on acute oxidative stress in Caenorhabditis elegans.
Albrecht's lab uses the tiny worm Caenorhabditis elegans (C.
vitripennis (83%-84%), Apis mellifera (82%), Acyrthosiphon pisum (79%), Tetranychus urticae (64%), Riphicephalus sanguineus (68%), Haemonchus contortus (45%-46%) and Caenorhabditis elegans (48%-51%) (Table 3).
However recent studies now use the model organism Caenorhabditis elegans, an organism with fundamental mechanisms and systems similar to the mammalian system.
1] Nonstandard abbreviations: miRNA, microRNA; qPCR, quantitative qPCR; cel-miR-39, Caenorhabditis elegans miR-39.
In line with these efforts, we have developed an HTS platform for environmental toxicants based on germline dysfunction in the roundworm Caenorhabditis elegans.
Among the experiments are detecting a lost chromosome, using mitochondrial DNA polymorphisms in evolutionary biology, detecting a transposon in corn, detecting genetically modified foods by polymerase chain reaction, and culturing and observing Caenorhabditis elegans.
Although it did not win a Golden Fleece Award, the more recent study of the mating behavior of the roundworm Caenorhabditis elegans seemed like another waste of time and money to some underinformed individuals.
One of these nematodes is Caenorhabditis elegans, and it is expected to be a good model for testing ricin toxicity because it is a eukaryote and therefore has the same types of ribosomes as humans.