Cabot-Locke murmur


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Cab·ot-Locke mur·mur

(kab'ŏt lok),
an early diastolic murmur, like that of aortic insufficiency, heard best at the left lower sternal border in severe anemia.

Cabot-Locke murmur

A near-extinct term for an early diastolic murmur heard along the left sternal border in patients with severe anaemia; it is not used in the working medical parlance, the approximate equivalent being a diastolic murmur mimicking aortic regurgitation.

Cabot,

Richard Clarke, U.S. physician, 1868-1939.
Cabot-Locke murmur - an early diastolic murmur, like that of aortic insufficiency, heard best at the left lower sternal border in severe anemia.
Cabot ring bodies - ring-shaped or figure-of-eight structures found in red blood cells in severe anemias. Synonym(s): Cabot rings
Cabot rings - Synonym(s): Cabot ring bodies

Locke,

Frank S., English physiologist, 1871-1949.
Cabot-Locke murmur - see under Cabot
Locke solutions - solutions used for irrigating and culturing mammalian heart and other tissues in laboratory experiments.
Locke-Ringer solution - a solution used in the laboratory for physiological and pharmacological experiments.