CAMK1

(redirected from CaM kinase I)

CAMK1

A gene on chromosome 3p25.3 that encodes the alpha subunit of a calcium/calmodulin-dependent protein kinase, which is part of the calcium-triggered CaMKK-CaMK1 signalling cascade and, upon calcium influx, regulates transcription activation, cell cycling, hormone production, cell differentiation, actin filament organisation and neurite outgrowth.
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For the study, researchers used rabbit heart cells, which behave much like human heart cells, and demonstrated that if CaM kinase is prevented from interacting with a protein that regulates calcium channels, negative effects, including cell death, do not occur.