PPIB

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PPIB

A gene on chromosome 15q21-q22 that encodes peptidylprolyl cis-trans isomerase B (cyclophilin B), which, as with other PPIs, accelerates protein folding. It catalyses the cis-trans isomerisation of proline-imidic peptide bonds in oligopeptides.

Molecular pathology
Defects in PPIB cause osteogenesis imperfecta type 9.