CYP 2E1

microsomal enzyme that participates in the oxidation of ethanol and acetaminophen. Inhibited by disulfiram and induced by ethanol and isoniazid (INH). Believed to be responsible for the hepatotoxic metabolite of acetaminophen.

CYP 2E1

Abbreviation for a microsomal enzyme that participates in the oxidation of ethanol and acetaminophen. Inhibited by disulfiram and induced by ethanol and isoniazid (INH). Believed to be responsible for the hepatotoxic metabolite of acetaminophen.

References in periodicals archive ?

There are experimental data showing that dry extract from Silybum marianum significantly inhibited a number of CYPs including CYP 3A4 and CYP 2E1 (Doehmer et al.

Propolis protects CYP 2E1 enzymatic activity and oxidative stress induced by carbon tetrachloride.

Protective effects of the apigenin-O/C-diglucoside saponarin from Gypsophila trichotoma on carbone tetrachloride-induced hepatotoxicity in vitro/in vivo in rats

Rabbit polyclonal antibody CYP 2E1 and HO-1 was provided by Santa Cruz (California.

Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO

5 [micro]M Source Sigma- Sigma- Aldrich Aldrich Incubation time 45 min 45 min Excitation wavelength 410 390 Emission wavelength 460 460 CYP 2E1 3A4 Amount Enzyme/ 2.

Effects of Kava (Kava-kava, 'Awa, Yaqona, Piper methysticum) on c-DNA-expressed cytochrome P450 enzymes and human cryopreserved hepatocytes

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