CXCR4 coreceptor

CXCR4 coreceptor

A cell surface receptor found on T cells that facilitates entry of HIV-1into these cells.
Synonym: fusin
See also: coreceptor
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References in periodicals archive ?
Trofile is a clinically validated patient selection tropism assay that determines whether a patient is infected with a strain of HIV that uses either the CCR5 coreceptor, the CXCR4 coreceptor, or a combination of CCR5 and CXCR4 to enter cells.
Scientists have genetically engineered mice not to express the CXCR4 coreceptor.
Trofile is a patient selection co-receptor tropism assay that determines whether a patient is infected with a strain of HIV that uses either the CCR5 coreceptor, the CXCR4 coreceptor, or a combination of CCR5 and CXCR4 to enter cells.