CXCL3


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CXCL3

A gene on chromosome 4q21 that encodes a chemokine with chemotactic activity for neutrophils. CXCL3 may play a role in inflammation and act on endothelial cells in an autocrine fashion.
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The highest increase of more than 1,700-fold was found for CXCL5 followed by CXCL2 and CXCL3 in adipose.
Expression of CXCL1, CXCL2, CXCL3, CXCL5, CXCL7, and CXCL14 in liver, lung, kidney, adipose, spleen, and thymus of C57BL/6 mice wt and AhRR Tg male mice in response to TCDD.
The CXCL3 (GRO-[gamma]) gene is a member of a gene superfamily encoding a set of related cytokines with inflammatory and growth regulatory properties (Haskill et al.