CXCL14


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CXCL14

A gene on chromosome 5q31 that encodes a CXC-type chemokine that is a potent chemoattractant for neutrophils, and weaker one for dendritic cells. It is not chemotactic for T cells, B cells, monocytes, natural killer cells or granulocytes.
References in periodicals archive ?
Expression of CXCL1, CXCL2, CXCL3, CXCL5, CXCL7, and CXCL14 in liver, lung, kidney, adipose, spleen, and thymus of C57BL/6 mice wt and AhRR Tg male mice in response to TCDD.
In contrast to ALK+ ALCL, there was also lower expression of cytotoxic molecules, cathepsins, and Th17 cell-associated molecules, and higher expression of some cytokines/receptors (CCL1, CCL22, CCR8, CCR4, IL-13RA2, CXCL14, TGF-bR1) and antiapoptotic molecules (BCL2, BIRC6, BIC), and lower expression of some proapoptotic genes (BAX, BCL2L1, BNPIP3).
It has been shown in vitro that angiostatic factors, such as thrombospondin-1 and the chemokines CXCL4 and CXCL14, appear to enhance DC maturation and APC function.