NKX2-5

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NKX2-5

A gene on chromosome 5q34 that encodes a homeobox transcription factor implicated in commitment to, and/or differentiation of, the myocardial lineage. It acts as a transcriptional activator of ANF in co-operation with GATA4.

Molecular pathology
NKX2-5 mutations cause atrial septal defect with atrioventricular conduction defect, tetralogy of Fallot, and congenital hypothyroidism non-goitrous type 5.
References in periodicals archive ?
The social media channels used by CSX may be updated from time to time.
In the CSX case, the taxpayer had argued that the payments were SUB payments because the employees receiving them had already been laid off and these payments had simply changed the employees' involuntary separation status from indefinite to permanent.
Fogarty joined CSX in 1989, following a distinguished career in government service, including serving as secretary of transportation and later as chief of staff for the Governor of Virginia.
The Mayor commended Staten Island Borough President Guy Molinari for "pressing these new initiatives and other economic development opportunities so vital to Staten Island, and for his efforts in helping secure this CSX property.
I never thought I'd live to see them put them back,'' said Mayor Todd Shininger, who retired as a signal foreman after 45 years with what once was the B&O, then the Baltimore & Ohio/Chesapeake & Ohio, then the Chessie System and finally, CSX.
While it's inevitable that a profitable company like CSX will pay plenty in taxes, how, when and where those taxes are paid can have a big impact on the company's overall performance.
The State of South Carolina continues to be a magnet for new industry," said Clark Robertson, assistant vice president, regional development at CSX.
This decision is significant for any taxpayers that have paid employment taxes on severance payments similar to the CSX workforce reduction payments.
CSX and Conrail have signed an agreement that contains a $300 million breakup fee and bars either side from negotiating with any other bidder until 1999.
CSX is part of the top five percent out of the thousands of companies that submitted climate disclosures for this year's report.
Specifically, CSX raised the cash portion of its offer to $110 a share for 40 percent of Conrail stock, up about 19 percent from the $92.
Under the agreement, McLane will provide CSX with national convenience stores' shipment data by category, and CSX subscribers will be able to view these trends on CSX's 24/7 online database.