retinal vasculopathy with cerebral leukodystrophy

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retinal vasculopathy with cerebral leukodystrophy

A microvascular endotheliopathy of the retina (OMIM:192315) of middle-age onset characterised by telangiectasias, microaneurysms and retinal capillary obliteration beginning in the macula, and microinfarcts of cerebral white matter that often coalesce to form pseudotumours.

Molecular pathology
Caused by defects of TREX1, which encodes a nuclear protein with 3' exonuclease activity.
References in periodicals archive ?
At CRV and DRV, we are excited about teaming up with such strong financial partners as Thor and Heartland.
One comparison sees the 2016 Honda CRV take on the 2016 Jeep Compass, which results in a landslide victory for the CRV thanks to its superior fuel efficiency, power and cargo capacity.
CRV wants to be a leading party in herd management, and to this end, we're keen to co-operate with innovative partners in this field," said Jos Koopman, Director of CRV West-Europe.
This car has always been well received and, throughout the three previous generations, the CRV has gained 140 awards worldwide since its launch in 1995.
They are to i) come to agreement on a reasonable but optimistic valuation of FantasyNet so that he can receive the $8 million investment from CRV while minimizing the equity he needs to relinquish for the funding, ii) maintain as much control of the company as possible, and iii) minimize the loss-of-control effects on him, as the founder and CEO, of any adverse turn of events in the performance of the company.
The bill will also accelerate, but not increase, the CRV payment that wholesalers pay, Mr.
Paterson cites the example of Honda dealers that had reported increased consumer enquiries about used examples of the current-shape CRV, keen to part-exchange larger and thirstier off-roaders including Range Rovers and BMW X3s.
The Ebbw Vale plant currently produces oil and water pumps for Honda Civic and CRV models produced in Swindon and for Opel Astra, Corsa and Zafira models made by Isuzu in Eastern Europe.
Between 1998 and February 2000, the state paid Segal and his businesses for bottles and cans that were not eligible under the CRV program, prosecutors said.
HONDA has announced the latest edition of the CRV sport-utility-vehicle.
An 11-year-old boy and his classmate were in Field Road, Bloxwich, at around 8am yesterday when a VW transporter van and a Honda CRV car collided.