CRLF2

(redirected from CRL2)

CRLF2

A gene on chromosome Xp22.3 and Yp11.3 that encodes a protein receptor for thymic stromal lymphopoietin (TSLP), which forms a functional complex with TSLP and IL7R and stimulates cell proliferation by activating STAT3 and STAT5, as well as JAK2. It is
implicated in the development of the haematopoietic system.
References in periodicals archive ?
sapiens) cytokine receptor-like factor 2; cytokine receptor CRL2 precursor 213258_at TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 244848_at CDNA FLJ31075 fis, clone HSYRA2001484 235889_at Homo sapiens transcribed sequence with moderate similarity to protein ref:NP_060312.