Patients with CRKP were categorized as the case group, while patients with only CSKP were categorized as the control group.
CRKP was defined as an isolate with ertapenem (MICs ≥2 [micro]g/ml), or imipenem and/or meropenem (MICs ≥4 [micro]g/ml).
Since January 2010, infection control nurses assigned from the Hospital Infection Control Committee (HICC) have performed active surveillance of CRKP and vancomycin-resistant enterococci (VRE) rectal colonization in selective high risk wards, including pediatric and neonatal intensive care units (PICU and NICU, respectively).
The data collected from patients with CRKP colonization included demographics, hospital unit at the time of CRKP detection, underlying diseases, invasive procedures within previous four weeks, duration and types of antibiotics use, absolute neutrophil and lymphocyte count at the time of colonization, and type of CRKP infection.
Similar to the GES-5 CRKP isolate from Sao Paulo, the MICs of carbapenems in the transformant dramatically declined to susceptibility levels for meropenem and doripenem, but to 1.
In summary, we report a second CRKP carrying the [bla.
In contrast, the lower prevalence of CRKP in our study might have resulted from a wider variety of institution types and inclusion of isolates from hospital patients outside of the critical care setting.
The low cross-resistance to tetracycline among CRKP and stable resistance rate of K.
Risk factors for CRKP were assessed by performing exact conditional logistic regression to calculate exact odds ratio (OR) estimates and 95% confidence intervals for dichotomous variables.
Because of the small number of case-patients, risk factors for CRKP infection (Table 2) were evaluated by exact conditional logistic regression.
Since first described in North Carolina in 1999, CRKP has been identified in 24 states and is recovered routinely in certain hospitals in New York and New Jersey (3).
Patients with unrecognized CRKP colonization have served as reservoirs for transmission during health-care--associated outbreaks (7).