CRABP1

(redirected from CRABP-I)
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CRABP1

A gene on chromosome 15q24 that encodes a member of the retinoic acid-binding protein family thought to play a central role in retinoic acid-mediated differentiation and proliferation.
References in periodicals archive ?
Bovine CRABP-I transcripts were undetectable in undifferentiated intramuscular fibroblast-like cells, but were markedly induced during differentiation.
The level of CRABP-I transcripts increased by more than two-fold after RA treatment at low or high concentrations (Figure 5C); however, the expression of CRABP-II mRNA decreased by more than four-fold compared with cultures lacking RA (Figure 5D).
Moreover, we cloned CRABP-II in sirloin tissue and CRABP-I in adipose tissue, so perhaps CRABP-I is involved in the regulation of bovine adipogenesis.
We next determined the level of CRABP-I and -II mRNA during adipocyte differentiation of bovine intramuscular fibroblast-like cells.