a professor in the Duke Departments of Chemistry and Biochemistry, designed a molecule that could block the CPAF activity inside of human cells.
They found that when CPAF was blocked over time by their designed molecule, the protective home that the bacteria make for themselves within the infected cells degraded, and CPAF no longer could degrade the proteins in the cell that would normally mount an immune response to the infection.
Other programs that have used CPAF successfully appear to be recognizing the value of using a base fee.
The defense contractors interviewed at Fort Belvoir agreed in principle that in CPAF contracts, some amount of base fee for their best efforts would more clearly delineate the difference between payment for best efforts and payment for excellent performance (award fee), thereby reducing the criticism concerning the use of award fee contracts.
The fee provision in CPAF contracts consists of a base fee (which may be zero) and an award amount, which is based on the government's subjective evaluation of the contractor's performance in areas such as management, technical performance, cost, schedule, and so forth.
Some existing CPAF contracts may contain semi-annual (or shorter) review periods.
For example, let us take a look at a CPAF contract.
To illustrate a potential area of dispute in a CPAF environment, let's look at a hypothetical scenario involving a typical contract clause, in particular, the one employed by the Navy and a shipbuilder pursuant to the design-and-build LPD 17 contract.