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COX-2 inhibitor
(redirected from COX-2 inhibition)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
COX-2 inhibitor (kkst)
n.
Any of a class of nonsteroidal anti-inflammatory drugs that cause fewer gastrointestinal side effects by selective inhibition of prostaglandin formation.

COX-2 inhibitor
Cyclooxygenase-2 inhibitor Pain management A class of analgesics with fewer side effects than those of conventional NSAIDs–which inhibit both cyclooxygenases–COX-1 and COX-2; COX-1 protects the gastric mucosa, preventing ulcers, bleeding, and other digestive tract problems. See COX-2, Prostaglandin.


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Measurement of COX-2 inhibition activity COX-2 activity was quantified using COX-2 inhibitors assays according to the manufacturer's instructions.
Selective COX-2 inhibition reduces vascular prostacyclin synthesis without disrupting COX-1-derived thromboxane synthesis in platelets.
The anti-angiogenic effect of turmeric compounds can be explained by the aforementioned selective COX-2 inhibition with curcuminoids.
 
 
 
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