CORIN


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CORIN

A gene on chromosome 4p13-p12 that encodes a serine-type endopeptidase which converts non-functional propeptide NPPA into active atrial natriuretic peptide hormone, resulting in natriuresis, diuresis and vasodilation. CORIN may also process pro-NPPB, the B-type natriuretic peptide.

Molecular pathology
Defects in CORIN cause pre-eclampsia/eclampsia type 5.
References in periodicals archive ?
and investigated the role of cardiomyocytes, corin and cardiac natriuretic peptide signaling in heart failure and the potential of treatment with PL-3994.
Optimized Ortho offers Corin the capability to present surgeons and patients a unique, customized, patient-specific solution for hip surgery that improves implant positioning and functional outcome.
She said: "I always considered Corin and Carrie to be musical soul-mates in the tradition of the greats.
I'm not going to put the go-ahead run on base,'' Worcester manager Justin Edwards said when asked if he made a mistake pitching to Corin with two outs and a runner on first.
ON THE WATER: Angela Molyneux, Jacki Doyle and Corin Bamford battle it out on Bowshaw reservoir (s)
DEATH MacD hono first d ye y ste Co mum sma has from A thr sp Tr Tra Corin, 10, who lost his mum and big sister in the smash early this month, has just been released from hospital.
Every single member of the team have an excellent chance of reaching the finals with Corin Clark already proving her credentials at the recent World Cup in Albacete (Spain) where she achieved gold and silver in the trampoline and synchronised trampoline events respectively.
Corin Timson became locked in a legal argument with cabbie Gary Phillips over several months of unpaid fares.
1-108] is produced in the heart, where corin and/or furin converts it to active BNP, which is then secreted by the heart into the circulation (4-6).
Her death aged 67 is the latest tragedy to strike the acting dynasty, coming less than a month after her brother Corin, 70, died.
Her death comes a year after her niece Natasha Richardson died from head injuries sustained in a skiing accident and only a month after the death of her older brother, Corin Redgrave.
A member of the famous acting dynasty, Redgrave was sister to Vanessa and Corin and the daughter of actor and director Sir Michael.