Side effects of COMT inhibitors
include nausea, vomiting, diarrhoea and abdominal pain.
Contract award: Supply of open-house discount contracts for drugs with the drug combination levodopa / decarboxylase inhibitor / comt inhibitors
(levodopa / carbidopa / entacapone) = atc n04ba03.
Also find individual revenue predictions to 2024 for five therapeutic submarkets at world level: -- Dopaminergic agents -- Dopamine receptor agonists -- COMT inhibitors
-- MAO inhibitors -- Treatments with other modes of action (grouped).
To some extent this can be addressed by administering MAO-B or COMT inhibitors
as part of therapy.
The number of subjects receiving COMT inhibitors
concomitant with L-dopa therapy was 12 (52.
The claim that this may prevent later motor complications needs to be further substantiated, but there may be a role for early introduction of COMT inhibitors
On the other hand, we found no significant role of COMT inhibitors
in sparing SAM or lowering tHcy in L-dopatreated patients.
11) COMT inhibitors
also increase "on" time and reduce "off" time in patients with motor fluctuations.
They believe that one way could be to offer targeted therapies with drugs like COMT inhibitors
to carriers of the gene.
our novel series of COMT inhibitors
for Parkinson's disease confirms our
There are four different types of drugs - levodopa, dopamine agonists, MAOB inhibitors and COMT inhibitors
- and within each class, more than one drug is available.
exist, but the one that gets into the brain has been noted for its liver toxicity.