PRKAR1A

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PRKAR1A

A gene on chromosome 17q23-q24 that encodes one of the regulatory subunits that comprise cAMP-dependent protein kinase. This enzyme transduces activating signals by phosphorylating different target proteins. PRKAR1A downregulates expression of liver genes in hepatoma/fibroblast hybrids.

Molecular pathology
PRKAR1A mutations cause Carney complex; it can fuse to the RET proto-oncogene by gene rearrangement and form PTC2, a  thyroid tumour-specific chimeric oncogene.
References in periodicals archive ?
This wide spread 158 pages report on CNC router market provides profiles of companies active in the CNC router industry, their product specifications, applications, their contact profiles and information, which form a fundamental part of the report.
The homogenous dispersion of CNC in chloroform was achieved through sequential solvent exchange process from water to acetone and subsequently to chloroform by centrifugation at each step at ~ 10,000 rpm.
The Marine Corps and Air Force identified the benefits of CNC capabilities before the Army did.
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The process planning presumes a laminated workpiece of (c)102 mm diameter and 122 mm length and involves only CNC machine tools.
The CNC operator-interface using Web-browser technology lets the maintenance supervisor connect to the CNC and view the interface directly from an office PC.
This saves time and effort by eliminating the need to make copies of the solid tool, so that core and cavity solids for a mold can be created much more quickly, CNC says.
With the WTO entry, signs look promising for a more stable environment for CNC and other companies, too, particularly since the government's highest priority now is state-of-the-art technology and a world-class business environment.
Factors driving the growth of CNC machine tools market in India are also explained in detail.
The 2014 Deep Research Report on Global and China CNC Spindle Industry introduces CNC Spindle with basic information including CNC Spindle definition classification application industry chain structure industry overview; international market analysis, China domestic market analysis, Macroeconomic environment and economic situation analysis, CNC Spindle industry policy and plan, CNC Spindle product specification, manufacturing process, cost structure etc.
8220;We are very pleased to present a website that functions as a value-added resource for prospective students as well as existing students,” said Melinda Keway, Director of Epic CNC Training Academy.