cytomegalovirus retinitis

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Related to CMV retinitis: Acute Retinal Necrosis

retinitis

 [ret″ĭ-ni´tis]
inflammation of the retina.
retinitis circina´ta (circinate retinitis) circinate retinopathy.
cytomegalovirus retinitis opportunistic infection of the retina by cytomegalovirus, seen in immunocompromised patients; symptoms include retinal necrosis and hemorrhage, leading to blindness.
exudative retinitis exudative retinopathy.
retinitis pigmento´sa a group of diseases, frequently hereditary, marked by progressive loss of retinal response (as recorded by the electroretinograph), retinal atrophy, attenuation of retinal vessels, and clumping of the pigment, with contraction of the field of vision. It may be transmitted as a dominant, recessive, or X-linked trait and is sometimes associated with other genetic defects. It may become manifest at the age of two or three years, or it may follow a slow course over a period of years. There is no successful treatment or cure for the condition. Early diagnosis allows the patient to prepare for the eventual loss of vision.
retinitis proli´ferans a condition that may result from intraocular hemorrhage, with neovascularization and the formation of fibrous bands extending into the vitreous from the retina; retinal detachment may result.
suppurative retinitis retinitis due to pyemic infection.

cytomegalovirus retinitis

Ophthalmology CMV infection of the eye, a common opportunistic infection in AIDS, a complication of disseminated CMV infection Clinical Retinal inflammation, blindness Management Antivirals–eg, foscarnet, cidofovir, gancyclovir, systemically and as a ganciclovir implant Prognosis Without treatment, retinal necrosis, vision loss

cytomegalovirus retinitis

Abbreviation: CMV retinitis
The most common eye infection in patients with acquired immunodeficiency syndrome. This opportunistic infection is responsible for visual impairment and blindness if left untreated.
See also: retinitis

retinitis, cytomegalovirus (CMV retinitis) 

A rare, chronic, diffuse infection of the retina caused by the cytomegalovirus (CMV), a member of the herpesvirus group. It affects people with an impaired immune system as a result of either AIDS, organ transplantation or chemotherapy for some malignancies such as leukaemia. The signs are whitish retinal lesions, which look granular (not fluffy, cotton-wool spots). These lesions progress into retinal necrosis with absolute visual field loss in that area. The lesions are usually accompanied by haemorrhages. Eventually the lesions coalesce and involve the entire fundus, resulting in complete visual loss. In the initial phase of the disease most patients are usually asymptomatic while those with symptoms will complain of floaters, blurred vision, photopsia, scotomas, metamorphopsia, etc. In some cases, retinal detachment follows the disease. Treatment with dihydroxy propoxymethyl guanine and ganciclovir produces some regression of the disease. See acquired immuno-deficiency syndrome.
References in periodicals archive ?
A diagnosis of CMV retinitis in the left eye and HIV retinopathy in the right eye was concluded.
All cases were evaluated to identify possible risk factors for the development of CMV retinitis.
CMV retinitis and other posterior segment manifestations were seen only in patients with <50 cells/uL.
Laboratory diagnosis of CMV retinitis was confirmed with positive results of serologic testing for CMV (IgM and IgG) along with CD4 count of 68 cells/cumm.
All the active cases of CMV retinitis had CD4-count less than 100 cells/[mm.
The widespread availability of HAART has significantly decreased the rates of opportunistic infections, including CMV retinitis [3].
The recommended dose for induction in patients with active CMV retinitis is 900 mg twice daily for 21 days taken with food.
The authors valued the global CMV retinitis therapeutics market at $525m in 2010, and forecasts it to decline at a negative CAGR of 3.
CMV retinitis is the most common cause of vision loss in patients with AIDS.
CMV retinitis was found in the majority of referred children with probable systemic CMV infection.
CMV retinitis was diagnosed by opthalmologist Data thus obtained was statistically analyzed.
The most commonly recognised manifestation of CMV is CMV retinitis (CMV-R), but pneumonitis, colitis, oesophagitis, adrenalitis, and neurological involvement are also described.