KIF1B

(redirected from CMT2)

KIF1B

A gene on chromosome 1p36.2 that encodes a motor protein that transports mitochondria and synaptic vesicle precursors.

Molecular pathology
KIF1B mutations cause Charcot-Marie-Tooth disease, type 2A1.
References in periodicals archive ?
The basis of this recommendation is classifying CMT according to the NCV findings into CMT1, CMT2, or intermediate between CMT1 and CMT2.
9) CMT sub-type, n (%) CMT1A 11 (73) 11 (73) CMTX 4 (27) 1 (7) Dejerine-Sottas syndrome 0 (0) 1 (7) Spinal CMT 0 (0) 1 (7) CMT2 0 (0) 1 (7) CMT = Charcot-Marie-Tooth disease, Exp = experimental group, Con = control group Table 2.
En yaygin formlan CMT1, CMT2, CMT3, CMT4 ve CMTX'tir (1).
CMT has been separated historically into two distinct clinical/pathological categories, CMT1 and CMT2, which are further subdivided according to genetic mapping criteria into -A, -B, -C, and so forth.