critical limb ischaemia

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critical limb ischaemia

; CLI advanced peripheral arterial disease (PAD); ischaemia so severe that limb viability is threatened (Table 1)
Table 1: Criteria used to define critical limb ischaemia
CriterionFeatureComment
1PainPersistent and regular rest pain persisting for > 2 weeks, requiring regular analgesia
Systolic pressuresAnkle < 50 mmHg; toe < 30 mmHg
2Tissue statusUlceration and/or gangrene of the foot/toes
Systolic pressuresAnkle < 50 mmHg; toe < 30 mmHg

Two criteria are used to define critical limb ischaemia: criterion 2 is especially applicable to patients, such as diabetics, with sensory neuropathy.

References in periodicals archive ?
Na Slovensku sa tvorbou CLI (Composite Leading Indicator) venuje Infostat, ktory skuma hospodarsky cyklus simultanne z dvoch hia-disk, a to prostrednictvom klasickeho cyklu aj rastuceho cyklu [16], [21].
Stekler (1991) used the 1983 version of the CLI (then produced by the Bureau of Economic Analysis, BEA) to calculate its leads and lags relative to the economy's cyclical turning points as identified by the National Bureau of Economic Research (NBER).
Testing the hypothesis that the roundedness of CLI peaks helps explain why obtaining advance warning of recessions is so difficult involves regressing the recognition lag at CLI turning points against alternative measures of roundedness.
This year, CLI is planning 10 new projects in Cebu alone, consisting of two residential subdivisions, three residential condominiums, three offices, one hotel and one industrial park.
Pluristem reached an agreement with Japan's Pharmaceuticals and Medical Devices Agency (PMDA) on the protocol of a pivotal trial in 75 patients for PLX-PAD in CLI via Japan's accelerated regulatory pathway for regenerative medicine.
Tim Mayleben, president and chief executive officer of Aastrom, said that Fast Track designation is an important step in the company's CLI programme and underscores the importance of finding an effective treatment option for this devastating disease.
Under Katz's leadership, the organization became a national leader in early childhood literacy and has implemented its research-proven CLI Model Classroom[TM] program, which provides training, coaching, and resources to K-3 teachers and principals in schools nationwide.
CLI is a chronic condition that results in severe pain in the feet or toes, as well as skin ulcers.
CLI remains an unmet clinical problem and with an ageing population and the rise in type 2 diabetes, the incidence of CLI is expected to increase.
The Townsend grant will also help fund the development of a CLI Model Classroom Portal providing established teachers with materials and strategies for creating literacy-rich classroom environments.
CLI planned to file early next year an application for the shelf registration of P10 billion worth of bonds, the first tranche of which would likely amount to P3 billion for prospective issuance by April or May 2018, CLI chief financial officer Stephen Tan told reporters in a recent interview.