CLEC4C

(redirected from CLECSF11)

CLEC4C

A gene on chromosome 12p13.2-p12.3 that encodes a C-type lectin domain protein involved in antigen capture, targeting ligands to peptide-loading compartments for presentation to T-cells. CLEC4C may downregulate IFN-alpha/beta expression in plasmacytoid dendritic cells; it may also act as a signalling receptor, activating protein-tyrosine kinases and mobilising intracellular calcium.