KRT4

(redirected from CK4)

KRT4

A gene on chromosome 12q13.13 that encodes a type-II cytokeratin that is specifically co-expressed in differentiated layers of mucosal and oesophageal epithelia with family member KRT13.

Molecular pathology
KRT4 mutations are associated with white sponge nevus, which is characterised by oral, oesophageal and anal leukoplakia.
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3] % % % 1 2 3 4 5 CK0 1727 14,2 34,8 24,5 CK1 1684 18,5 36,5 31,1 CK2 1701 17,7 35,8 30,2 CK3 1672 18,5 36,9 30,9 CK4 1673 18,6 36,9 31,2 CK5 1672 18,7 36,9 31,3 CK6 1673 18,3 36,9 30,6 Poringumo Sudeties [P.
La diferencia entre los fenotipos epiteliales corneales y conjuntivos se basa en la expresion de diferentes queratinas --mucinas--, siendo las citoqueratinas CK4 y CK13 las que se expresan en el epitelio conjuntival (10).
2), and simple keratins (CKs 7, 8, and 19), but usually not CK4, CK5/CK6, and CK14.